Repeated Measurement Design for Phase I Clinical Trial

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Documentation for package ‘phase1RMD’ version 1.0.9

• DESCRIPTION file.

Help Pages

eff_dat	Patient efficacy data
GenToxProb	Toxicity Probability Matrices Generation for Trial Simulation
parm	Create prior for the phase 1 dose-finding model
patdata	Patient toxicity data
plot.RunRMDVal	plot nTTP Toxicity-based in cycle 1 for all doses.
probaT	The probability matrix of toxicity events
RunRMD	Toxicity-based Dose estimation for the next patient cohort.
RunRMDEFF	Interactive Implementation for an Adaptive, Multi-Stage Phase I Dose-Finding Design
SimRMD	Simulate trial characters of the phase I dose-finding design.
SimRMDEFF	Simulation for an Adaptive, Multi-Stage Phase I Dose-Finding Design
tox.matrix	Probability matrix for toxicity
Tox2nTTP	Compute the nTTP score baed on the observed toxicity.
tox_dat	Patient toxicity data
tox_dat_bytype	Patient toxicity data